nando_uri nando_id hum_uri hum_id label_ja label_en type_study_ja type_study_en type_data_ja type_data_en http://nanbyodata.jp/ontology/NANDO_1100001 NANDO:1100001 https://humandbs.dbcls.jp/hum0069 hum0069 神経筋疾患、ウイルス性疾患におけるRNA発現プロファイル解析 RNA expression profiling of neuromuscular diseases and viral diseases NGS (small RNA-seq) NGS (small RNA-seq) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1100001 NANDO:1100001 https://humandbs.dbcls.jp/hum0423 hum0423 マルチオミックス的アプローチによる炎症性筋疾患の全容解明 Comprehensive elucidation of inflammatory muscle diseases by multi-omics analysis NGS (RNA-seq、snRNA-seq) NGS (RNA-seq, snRNA-seq) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1100002 NANDO:1100002 https://humandbs.dbcls.jp/hum0365 hum0365 生活習慣病における腸内細菌の役割について The role of gut microbiota in metabolic diseases NGS (CAGE-seq) NGS (CAGE-seq) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1100005 NANDO:1100005 https://humandbs.dbcls.jp/hum0064 hum0064 高齢者がん治療アルゴリズム開発のためのガイドポスト・データベースの構築と必須情報及びその推定モデル Construction of Geriatric Oncology Database for establishment of the Treatment Algorithm: Clinical Data and Questionnaire Survey Results in JapaneseElderly Cancer Patients Retrospective study *サンガー TaqMan qRT-PCR マイクロアレイ COBRA 治療情報 臨床情報 Direct sequencing TaqMan qRT-PCR COBRA cDNA microarray Clinical data Treatment data 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1100005 NANDO:1100005 https://humandbs.dbcls.jp/hum0269 hum0269 遺伝性心血管疾患の感受性遺伝子解析研究 Sensitive gene analysis of hereditary cardiovascular disease NGS (Exome、RNA-seq) NGS (Exome, RNA-seq) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1100006 NANDO:1100006 https://humandbs.dbcls.jp/hum0382 hum0382 造血器疾患における遺伝子異常・エピジェネティクス異常の解析 Analysis of genetic and epigenetic abnormalities in hematopoietic diseases NGS (WGS) NGS (WGS) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1200002 NANDO:1200002 https://humandbs.dbcls.jp/hum0014 hum0014 オーダーメイド医療の実現プログラム Bio Bank Japan project SNP-chip NGS (WGS、Target Capture) SNP-chip Case-Control NGS (WGS, Target Capture) 非制限公開 制限(Type I) Unrestricted-access Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1200002 NANDO:1200002 https://humandbs.dbcls.jp/hum0018 hum0018 神経筋変性疾患の遺伝子解析研究 Genetic analysis in neurodegenerative disorders NGS (Exome、WGS、RNA-seq) NGS (Exome, WGS, RNA-seq) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1200002 NANDO:1200002 https://humandbs.dbcls.jp/hum0020 hum0020 筋萎縮性側索硬化症の遺伝子解析研究 Genetic Analysis in Amyotrophic Lateral Sclerosis NGS (Exome) NGS (Exome) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1200002 NANDO:1200002 https://humandbs.dbcls.jp/hum0484 hum0484 ヒト体細胞から樹立したInduced Pluripotent Stem Cell Line(iPS細胞株)のバンク事業 Banking of induced pluripotent stem cell lines (iPS cell lines) established from human somatic cells NGS (WGS) NGS (WGS) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1200010 NANDO:1200010 https://humandbs.dbcls.jp/hum0113 hum0113 パーキンソン病の代謝産物バイオマーカー創出およびその分子標的機構に基づく創薬シーズ同定 Development of metabolite biomarkers of Parkinson’s disease and identification of drug seeds from chemical screening based on the biomarkers NGS (CAGE-seq) NGS (CAGE-seq) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1200016 NANDO:1200016 https://humandbs.dbcls.jp/hum0018 hum0018 神経筋変性疾患の遺伝子解析研究 Genetic analysis in neurodegenerative disorders NGS (Exome、WGS、RNA-seq) NGS (Exome, WGS, RNA-seq) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1200020 NANDO:1200020 https://humandbs.dbcls.jp/hum0321 hum0321 胸腺組織を介した免疫系構築の遺伝子制御に関する研究 Comprehensive analysis of interaction between human gene expression and environmental metagenomes NGS (scRNA-seq) NGS (scRNA-seq) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1200020 NANDO:1200020 https://humandbs.dbcls.jp/hum0379 hum0379 制御性T細胞特異的エピゲノム誘導による免疫制御の研究 Immune regulation by cotrolling regulatory T cell-specific epigenome NGS (scRNA-seq、scVDJ-seq) NGS (scRNA-seq, scVDJ-seq) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1200023 NANDO:1200023 https://humandbs.dbcls.jp/hum0379 hum0379 制御性T細胞特異的エピゲノム誘導による免疫制御の研究 Immune regulation by cotrolling regulatory T cell-specific epigenome NGS (scRNA-seq、scVDJ-seq) NGS (scRNA-seq, scVDJ-seq) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1200027 NANDO:1200027 https://humandbs.dbcls.jp/hum0324 hum0324 脳血管障害及び神経筋難病の遺伝子解析研究 Genetic analysis of cerebrovascular diseases and neuromuscular disorders NGS (WGBS) NGS (WGBS) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1200032 NANDO:1200032 https://humandbs.dbcls.jp/hum0079 hum0079 神経筋変性疾患の遺伝子解析研究 Genetic analysis in neurodegeneraive disorders NGS (RNA-seq) NGS (RNA-seq) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1200033 NANDO:1200033 https://humandbs.dbcls.jp/hum0130 hum0130 POEMS症候群の骨髄細胞における遺伝子異常の網羅的解析 造血器腫瘍と骨髄ニッチ細胞の遺伝子異常解析による分子病態の解明と新規治療薬開発の基盤構築 Comprehensive genetic analyses of bone marrow cells in POEMS syndrome Analyses of molecular mechanisms of hematological malignancies and bone marrow niche NGS (Exome、Target Capture、RNA-seq、scRNA-seq) NGS (Exome, Target Capture, RNA-seq, scRNA-seq) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1200034 NANDO:1200034 https://humandbs.dbcls.jp/hum0018 hum0018 神経筋変性疾患の遺伝子解析研究 Genetic analysis in neurodegenerative disorders NGS (Exome、WGS、RNA-seq) NGS (Exome, WGS, RNA-seq) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1200044 NANDO:1200044 https://humandbs.dbcls.jp/hum0001 hum0001 SCA31罹患患者のゲノム解析データ Sequence Data of a SCA31 Patient NGS (WGS) Single Patient NGS (WGS) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1200052 NANDO:1200052 https://humandbs.dbcls.jp/hum0018 hum0018 神経筋変性疾患の遺伝子解析研究 Genetic analysis in neurodegenerative disorders NGS (Exome、WGS、RNA-seq) NGS (Exome, WGS, RNA-seq) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1200157 NANDO:1200157 https://humandbs.dbcls.jp/hum0221 hum0221 ヒト疾患特異的iPS細胞を用いた遺伝子解析研究 Genetic study using human disease-specific iPS cells NGS (RNA-seq) NGS (RNA-seq) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1200183 NANDO:1200183 https://humandbs.dbcls.jp/hum0351 hum0351 画像検査と RNF213 遺伝子検査の融合による閉塞性血管障害の新評価体系の確立 New classification of occlusive cerebrovascular diseases by combining diagnostic imaging and genetic analysis of RNF213 メタゲノム Metagenome 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1200206 NANDO:1200206 https://humandbs.dbcls.jp/hum0225 hum0225 HTLV-1関連脊髄症(HAM)におけるゲノム異常及びエピゲノム異常の解析 Mortality and risk of progression to adult T-cell leukemia/lymphoma in patients with HTLV-1-associated myelopathy/tropical spastic paraparesis NGS (Target Capture、RNA-seq、ATAC-seq、scRNA-seq、scATAC-seq) NGS (Target Capture, RNA-seq, ATAC-seq, scRNA-seq, scATAC-seq) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1200226 NANDO:1200226 https://humandbs.dbcls.jp/hum0271 hum0271 ハプロ不全により発症する常染色体優性遺伝性疾患における表現型発現の個体差に関する包括的ゲノム解析研究 Comprehensive genome analysis related to individual differences in phenotypic expression in autosomal dominant diseases caused by haploinsufficiency NGS (Target Capture、Target RNA-seq) NGS (Target Capture, Target RNA-seq) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1200228 NANDO:1200228 https://humandbs.dbcls.jp/hum0266 hum0266 患者検体を用いた自己免疫性皮膚疾患発症機序の解明 Elucidation of the pathogenesis of autoimmune dermatosis using patient samples. NGS (scRNA-seq) NGS (scRNA-seq) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1200245 NANDO:1200245 https://humandbs.dbcls.jp/hum0029 hum0029 Stevens-Johnson症候群に対する 遺伝子多型解析 Study of Genome Polymorphism/Variation on Stevens-Johnson Syndrome SNP-chip SNP-chip Case-Control 非制限公開 Unrestricted-access http://nanbyodata.jp/ontology/NANDO_1200246 NANDO:1200246 https://humandbs.dbcls.jp/hum0029 hum0029 Stevens-Johnson症候群に対する 遺伝子多型解析 Study of Genome Polymorphism/Variation on Stevens-Johnson Syndrome SNP-chip SNP-chip Case-Control 非制限公開 Unrestricted-access http://nanbyodata.jp/ontology/NANDO_1200251 NANDO:1200251 https://humandbs.dbcls.jp/hum0214 hum0214 ヒト免疫系の機能ゲノム学による統合的理解とこれを用いた免疫疾患の発症予防のためのインターベンション戦略の構築 Integrative understanding of human immune system by functional genomics and development of intervention strategies for the prevention of autoimmune diseases NGS (RNA-seq、scRNA-seq) eQTL B細胞受容体レパトア解析 NGS (RNA-seq, scRNA-seq) eQTL BCR repertoire analysis 非制限公開 制限(Type I) Unrestricted-access Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1200262 NANDO:1200262 https://humandbs.dbcls.jp/hum0416 hum0416 経時的な多層的オミックス解析を通した免疫難病及びがんにおける生体反応の解明と新規治療法の開発 Elucidation of biological responses in intractable immune disorders and cancer and development of novel therapies through sequential multilevel omics analysis. NGS (CITE-seq、BD Ab-seq、scRNA-seq) シングルセル空間トランスクリプトーム NGS (CITE-seq, BD Ab-seq, scRNA-seq) single-cell spatial transcriptome 非制限公開 Unrestricted-access http://nanbyodata.jp/ontology/NANDO_1200265 NANDO:1200265 https://humandbs.dbcls.jp/hum0393 hum0393 膠原病類縁疾患患者検体を用いた新規バイオマーカーおよび治療標的分子探索に関する研究 To explore new biomarkers or therapeutic target molecules using samples with patients with autoimmune diseases NGS (RNA-seq) NGS (RNA-seq) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1200272 NANDO:1200272 https://humandbs.dbcls.jp/hum0214 hum0214 ヒト免疫系の機能ゲノム学による統合的理解とこれを用いた免疫疾患の発症予防のためのインターベンション戦略の構築 Integrative understanding of human immune system by functional genomics and development of intervention strategies for the prevention of autoimmune diseases NGS (RNA-seq、scRNA-seq) eQTL B細胞受容体レパトア解析 NGS (RNA-seq, scRNA-seq) eQTL BCR repertoire analysis 非制限公開 制限(Type I) Unrestricted-access Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1200272 NANDO:1200272 https://humandbs.dbcls.jp/hum0379 hum0379 制御性T細胞特異的エピゲノム誘導による免疫制御の研究 Immune regulation by cotrolling regulatory T cell-specific epigenome NGS (scRNA-seq、scVDJ-seq) NGS (scRNA-seq, scVDJ-seq) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1200276 NANDO:1200276 https://humandbs.dbcls.jp/hum0079 hum0079 神経筋変性疾患の遺伝子解析研究 Genetic analysis in neurodegeneraive disorders NGS (RNA-seq) NGS (RNA-seq) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1200277 NANDO:1200277 https://humandbs.dbcls.jp/hum0214 hum0214 ヒト免疫系の機能ゲノム学による統合的理解とこれを用いた免疫疾患の発症予防のためのインターベンション戦略の構築 Integrative understanding of human immune system by functional genomics and development of intervention strategies for the prevention of autoimmune diseases NGS (RNA-seq、scRNA-seq) eQTL B細胞受容体レパトア解析 NGS (RNA-seq, scRNA-seq) eQTL BCR repertoire analysis 非制限公開 制限(Type I) Unrestricted-access Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1200277 NANDO:1200277 https://humandbs.dbcls.jp/hum0218 hum0218 全身性強皮症患者の遺伝子発現解析 Gene expression analysis in systemic sclerosis NGS (scRNA-seq) NGS (scRNA-seq) 非制限公開 Unrestricted-access http://nanbyodata.jp/ontology/NANDO_1200277 NANDO:1200277 https://humandbs.dbcls.jp/hum0416 hum0416 経時的な多層的オミックス解析を通した免疫難病及びがんにおける生体反応の解明と新規治療法の開発 Elucidation of biological responses in intractable immune disorders and cancer and development of novel therapies through sequential multilevel omics analysis. NGS (CITE-seq、BD Ab-seq、scRNA-seq) シングルセル空間トランスクリプトーム NGS (CITE-seq, BD Ab-seq, scRNA-seq) single-cell spatial transcriptome 非制限公開 Unrestricted-access http://nanbyodata.jp/ontology/NANDO_1200278 NANDO:1200278 https://humandbs.dbcls.jp/hum0214 hum0214 ヒト免疫系の機能ゲノム学による統合的理解とこれを用いた免疫疾患の発症予防のためのインターベンション戦略の構築 Integrative understanding of human immune system by functional genomics and development of intervention strategies for the prevention of autoimmune diseases NGS (RNA-seq、scRNA-seq) eQTL B細胞受容体レパトア解析 NGS (RNA-seq, scRNA-seq) eQTL BCR repertoire analysis 非制限公開 制限(Type I) Unrestricted-access Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1200279 NANDO:1200279 https://humandbs.dbcls.jp/hum0214 hum0214 ヒト免疫系の機能ゲノム学による統合的理解とこれを用いた免疫疾患の発症予防のためのインターベンション戦略の構築 Integrative understanding of human immune system by functional genomics and development of intervention strategies for the prevention of autoimmune diseases NGS (RNA-seq、scRNA-seq) eQTL B細胞受容体レパトア解析 NGS (RNA-seq, scRNA-seq) eQTL BCR repertoire analysis 非制限公開 制限(Type I) Unrestricted-access Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1200279 NANDO:1200279 https://humandbs.dbcls.jp/hum0416 hum0416 経時的な多層的オミックス解析を通した免疫難病及びがんにおける生体反応の解明と新規治療法の開発 Elucidation of biological responses in intractable immune disorders and cancer and development of novel therapies through sequential multilevel omics analysis. NGS (CITE-seq、BD Ab-seq、scRNA-seq) シングルセル空間トランスクリプトーム NGS (CITE-seq, BD Ab-seq, scRNA-seq) single-cell spatial transcriptome 非制限公開 Unrestricted-access http://nanbyodata.jp/ontology/NANDO_1200279 NANDO:1200279 https://humandbs.dbcls.jp/hum0492 hum0492 産学連携による免疫炎症性難病の新規医薬品開発を目指した探索研究 Exploratory research aimed at developing new drugs for difficult-to-treat immune-inflammatory diseases through industry-academia collaboration NGS (scRNA-seq/TCR/BCRレパトア解析、Visium Spatial Gene Expression) 病理画像 NGS (scRNA-seq/TCR/BCR repetoire, Visium Spatial Gene Expression) Histological image 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1200282 NANDO:1200282 https://humandbs.dbcls.jp/hum0214 hum0214 ヒト免疫系の機能ゲノム学による統合的理解とこれを用いた免疫疾患の発症予防のためのインターベンション戦略の構築 Integrative understanding of human immune system by functional genomics and development of intervention strategies for the prevention of autoimmune diseases NGS (RNA-seq、scRNA-seq) eQTL B細胞受容体レパトア解析 NGS (RNA-seq, scRNA-seq) eQTL BCR repertoire analysis 非制限公開 制限(Type I) Unrestricted-access Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1200284 NANDO:1200284 https://humandbs.dbcls.jp/hum0214 hum0214 ヒト免疫系の機能ゲノム学による統合的理解とこれを用いた免疫疾患の発症予防のためのインターベンション戦略の構築 Integrative understanding of human immune system by functional genomics and development of intervention strategies for the prevention of autoimmune diseases NGS (RNA-seq、scRNA-seq) eQTL B細胞受容体レパトア解析 NGS (RNA-seq, scRNA-seq) eQTL BCR repertoire analysis 非制限公開 制限(Type I) Unrestricted-access Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1200284 NANDO:1200284 https://humandbs.dbcls.jp/hum0416 hum0416 経時的な多層的オミックス解析を通した免疫難病及びがんにおける生体反応の解明と新規治療法の開発 Elucidation of biological responses in intractable immune disorders and cancer and development of novel therapies through sequential multilevel omics analysis. NGS (CITE-seq、BD Ab-seq、scRNA-seq) シングルセル空間トランスクリプトーム NGS (CITE-seq, BD Ab-seq, scRNA-seq) single-cell spatial transcriptome 非制限公開 Unrestricted-access http://nanbyodata.jp/ontology/NANDO_1200286 NANDO:1200286 https://humandbs.dbcls.jp/hum0404 hum0404 循環器疾患のゲノム解析技術、iPS細胞技術、ゲノム編集技術を用いた病態解明ならびに治療法開発研究 循環器疾患患者由来iPS細胞を用いた病態解明ならびに新規医療技術開発研究 Elucidation of pathology and therapeutic development using genome analysis, iPS cells, and genome editing for cardiovascular diseases Elucidation of pathology and development of novel medical technology using iPS cells derived from patients with cardiovascular disease NGS (scRNA-seq、WGS) NGS (scRNA-seq, WGS) 非制限公開 制限(Type I) Unrestricted-access Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1200295 NANDO:1200295 https://humandbs.dbcls.jp/hum0097 hum0097 骨髄不全症候群における血球の質に関する検討 Cytogenetic analysis of hematopoietic cells in bone marrow failure syndrome NGS (Exome) NGS (Exome) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1200295 NANDO:1200295 https://humandbs.dbcls.jp/hum0434 hum0434 T/NK細胞が関連する各種疾患における遺伝子解析 Genetic analyses in patients with T or NK cells-associated disorders NGS (Exome、Target Capture) NGS (Exome, Target Capture) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1200296 NANDO:1200296 https://humandbs.dbcls.jp/hum0097 hum0097 骨髄不全症候群における血球の質に関する検討 Cytogenetic analysis of hematopoietic cells in bone marrow failure syndrome NGS (Exome) NGS (Exome) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1200307 NANDO:1200307 https://humandbs.dbcls.jp/hum0378 hum0378 溶血性貧血の病態解明を目指した基礎研究 Basic research to elucidate the pathogenesis of hemolytic anemia NGS (Exome) NGS (Exome) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1200320 NANDO:1200320 https://humandbs.dbcls.jp/hum0101 hum0101 EBウイルス関連リンパ腫を発症した原発性免疫不全症候群の原因遺伝子探索に関する研究 Identification of gene mutations in primary immunodeficiency characterized by EBV-associated B-cell lymphoma NGS (Target Capture) NGS (Target Capture) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1200334 NANDO:1200334 https://humandbs.dbcls.jp/hum0368 hum0368 全ゲノム配列決定によるICF症候群の新規原因遺伝子の探索および機能解析 Identification and functional analysis of novel causative genes of ICF syndrome by whole genome sequencing NGS (PBAT-seq) NGS (PBAT-seq) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1200366 NANDO:1200366 https://humandbs.dbcls.jp/hum0476 hum0476 腎臓構成細胞の生物学的機能理解のための先端的解析技術を用いた観察研究 Observational studies using advanced analytical techniques to understand the biological functions of kidney component cells NGS (scRNA-seq、Visium Spatial Gene Expression) 病理画像 NGS (scRNA-seq, Visium Spatial Gene Expression) Histological image 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1200422 NANDO:1200422 https://humandbs.dbcls.jp/hum0406 hum0406 ヒト疾患特異的iPS細胞の作成とそれを用いた疾患解析に関する研究 The Generation of Human Disease-Specific iPS Cells and the Use of Such iPS Cells for Disease Analysis NGS (RNA-seq) NGS (RNA-seq) 非制限公開 制限(Type I) Unrestricted-access Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1200439 NANDO:1200439 https://humandbs.dbcls.jp/hum0076 hum0076 日本人原発性胆汁性肝硬変の発症・進展に関わる遺伝因子の網羅的遺伝子解析 Genome-wide search for susceptibility genes to primary biliary chirrosis SNP-chip SNP-chip 非制限公開 Unrestricted-access http://nanbyodata.jp/ontology/NANDO_1200439 NANDO:1200439 https://humandbs.dbcls.jp/hum0261 hum0261 原発性胆汁性胆管炎の病態解明のためのゲノムワイド関連解析 ― 1,000 症例の追加解析 ― Genome-wide association study of primary biliary cholangitis (PBC) -an additional study of 1,000 Japanese PBC patients- SNP-chip SNP-chip 非制限公開 Unrestricted-access http://nanbyodata.jp/ontology/NANDO_1200444 NANDO:1200444 https://humandbs.dbcls.jp/hum0125 hum0125 制御性T細胞特異的エピゲノム誘導による免疫制御の研究 Immune regulation by cotrolling regulatory T cell-specific epigenome NGS (RNA-seq) NGS (RNA-seq) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1200444 NANDO:1200444 https://humandbs.dbcls.jp/hum0166 hum0166 炎症性腸疾患患者におけるチオプリン関連副作用とNUDT15遺伝子多型との相関性に関する多施設共同研究(MENDEL Study) Multicenter Evaluation of NUDT15-R139C genotyping efficiency to DEtect thiopurine-induced hair Loss and leukopenia (MENDEL study) SNP-chip SNP-chip 非制限公開 制限(Type I) Unrestricted-access Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1200444 NANDO:1200444 https://humandbs.dbcls.jp/hum0197 hum0197 多層的オミクス解析による疾患病態の解明 Elucidation of disease state by multi-layered omics analysis メタゲノム SNP-chip NGS (WGS、RNA-seq、scRNA-seq) eHHV-6の有無、アネロウイルス量 プロテオミクス Metagenome SNP-chip NGS (WGS, RNA-seq, scRNA-seq) Presence or absence of endogenous herpesvirus 6, anellovirus load proteimics 非制限公開 制限(Type I) Unrestricted-access Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1200444 NANDO:1200444 https://humandbs.dbcls.jp/hum0454 hum0454 免疫異常に着目した炎症性腸疾患の病因解析および治療反応性解析 Etiological and therapeutic response analysis of inflammatory bowel disease focusing on immune abnormalities Xenium In Situ Gene Expression Xenium In Situ Gene Expression 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1200449 NANDO:1200449 https://humandbs.dbcls.jp/hum0166 hum0166 炎症性腸疾患患者におけるチオプリン関連副作用とNUDT15遺伝子多型との相関性に関する多施設共同研究(MENDEL Study) Multicenter Evaluation of NUDT15-R139C genotyping efficiency to DEtect thiopurine-induced hair Loss and leukopenia (MENDEL study) SNP-chip SNP-chip 非制限公開 制限(Type I) Unrestricted-access Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1200449 NANDO:1200449 https://humandbs.dbcls.jp/hum0197 hum0197 多層的オミクス解析による疾患病態の解明 Elucidation of disease state by multi-layered omics analysis メタゲノム SNP-chip NGS (WGS、RNA-seq、scRNA-seq) eHHV-6の有無、アネロウイルス量 プロテオミクス Metagenome SNP-chip NGS (WGS, RNA-seq, scRNA-seq) Presence or absence of endogenous herpesvirus 6, anellovirus load proteimics 非制限公開 制限(Type I) Unrestricted-access Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1200449 NANDO:1200449 https://humandbs.dbcls.jp/hum0454 hum0454 免疫異常に着目した炎症性腸疾患の病因解析および治療反応性解析 Etiological and therapeutic response analysis of inflammatory bowel disease focusing on immune abnormalities Xenium In Situ Gene Expression Xenium In Situ Gene Expression 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1200464 NANDO:1200464 https://humandbs.dbcls.jp/hum0129 hum0129 神経疾患患者からのiPS細胞の樹立とそれを用いた疾患解析に関する研究 Research for analyzing mechanistic insight into disease progression of neural disease based on iPS cell technology NGS (ChIP-seq) NGS (ChIP-seq) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1200495 NANDO:1200495 https://humandbs.dbcls.jp/hum0404 hum0404 循環器疾患のゲノム解析技術、iPS細胞技術、ゲノム編集技術を用いた病態解明ならびに治療法開発研究 循環器疾患患者由来iPS細胞を用いた病態解明ならびに新規医療技術開発研究 Elucidation of pathology and therapeutic development using genome analysis, iPS cells, and genome editing for cardiovascular diseases Elucidation of pathology and development of novel medical technology using iPS cells derived from patients with cardiovascular disease NGS (scRNA-seq、WGS) NGS (scRNA-seq, WGS) 非制限公開 制限(Type I) Unrestricted-access Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1200495 NANDO:1200495 https://humandbs.dbcls.jp/hum0514 hum0514 骨格筋メッセンジャーRNAの発現解析による神経・筋疾患の病態解明 Analysis of skeletal muscle messenger RNA expression to elucidate pathophysiology of neuromuscular diseases NGS (RNA-seq) NGS (RNA-seq) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1200549 NANDO:1200549 https://humandbs.dbcls.jp/hum0018 hum0018 神経筋変性疾患の遺伝子解析研究 Genetic analysis in neurodegenerative disorders NGS (Exome、WGS、RNA-seq) NGS (Exome, WGS, RNA-seq) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1200552 NANDO:1200552 https://humandbs.dbcls.jp/hum0347 hum0347 急性脳症の包括的遺伝子解析 Comprehensive genetic analysis of acute encephalopathy サンガー法 SNP-chip Sanger-seq SNP-chip 非制限公開 Unrestricted-access http://nanbyodata.jp/ontology/NANDO_1200607 NANDO:1200607 https://humandbs.dbcls.jp/hum0375 hum0375 超高速DNAシーケンサーを用いた疾患原因ゲノム領域の同定と情報解析法の確立、および参照配列データの作成に関する研究 identification of disease responsible genome region and establishment of genome information technology by next generation DNA sequencer NGS (Exome) NGS (Exome) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1200633 NANDO:1200633 https://humandbs.dbcls.jp/hum0163 hum0163 精神・神経疾患治療薬及びがん治療薬におけるファーマコゲノミクス研究 Pharmacogenomics research for therapeutics in psychiatry, neurology and oncology NGS (Target Capture) SNP-chip NGS (Target Capture) SNP-chip 非制限公開 Unrestricted-access http://nanbyodata.jp/ontology/NANDO_1200655 NANDO:1200655 https://humandbs.dbcls.jp/hum0302 hum0302 iPS細胞の高次特性解析と加工iPS細胞の作製 iPS Cell Advanced Characterization and Development of modified iPS cells NGS (RNA-seq) NGS (RNA-seq) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1200664 NANDO:1200664 https://humandbs.dbcls.jp/hum0131 hum0131 発達障害のエピゲノム解析 The epigenetics of neurodevelopmental disorders NGS (RNA-seq) NGS (RNA-seq) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1200719 NANDO:1200719 https://humandbs.dbcls.jp/hum0126 hum0126 小児ネフローゼ症候群の疾患感受性遺伝子及び薬剤感受性遺伝子同定研究 Identification of the disease and drug susceptibility genes for the Childhood Idiopathic Nephrotic Syndrome SNP-chip SNP-chip 非制限公開 Unrestricted-access http://nanbyodata.jp/ontology/NANDO_1200747 NANDO:1200747 https://humandbs.dbcls.jp/hum0197 hum0197 多層的オミクス解析による疾患病態の解明 Elucidation of disease state by multi-layered omics analysis メタゲノム SNP-chip NGS (WGS、RNA-seq、scRNA-seq) eHHV-6の有無、アネロウイルス量 プロテオミクス Metagenome SNP-chip NGS (WGS, RNA-seq, scRNA-seq) Presence or absence of endogenous herpesvirus 6, anellovirus load proteimics 非制限公開 制限(Type I) Unrestricted-access Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1200889 NANDO:1200889 https://humandbs.dbcls.jp/hum0434 hum0434 T/NK細胞が関連する各種疾患における遺伝子解析 Genetic analyses in patients with T or NK cells-associated disorders NGS (Exome、Target Capture) NGS (Exome, Target Capture) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1200903 NANDO:1200903 https://humandbs.dbcls.jp/hum0008 hum0008 ヒルシュスプルング病および ヒルシュスプルング類縁疾患の 遺伝要因および発症機構解明に関する研究 Research for genetic causes and mechanisms of Hirschsprung's   NGS (Exome) NGS (Exome) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1200913 NANDO:1200913 https://humandbs.dbcls.jp/hum0486 hum0486 胆道閉鎖症およびアラジール症候群特異的iPS細胞を用いた胆管発生およびその障害メカニズムの解明 Bile duct development and its failure mechanisms using biliary atresia and Alagille syndrome-specific iPS cells NGS (WGS) NGS (WGS) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1200941 NANDO:1200941 https://humandbs.dbcls.jp/hum0005 hum0005 難聴の遺伝子解析と臨床応用に関する研究 Genetic Analysis of Hearing Loss and Its Clinical Application NGS (Target Capture) NGS (Target Capture) 非制限公開 制限(Type I) Unrestricted-access Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_1201001 NANDO:1201001 https://humandbs.dbcls.jp/hum0508 hum0508 疾患特異的iPS細胞を用いた眼疾患の発症機序の解明および治療法の探索 Elucidation of the pathogenesis of ocular diseases and exploration of therapeutic strategies using disease-specific iPS cells NGS (scRNA-seq) NGS (scRNA-seq) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2100002 NANDO:2100002 https://humandbs.dbcls.jp/hum0022 hum0022 同種造血幹細胞移植後 ドナー由来白血病発症にかかわる 分子機構の解析 Analysis of the Molecular Mechanism for Developing Donor-Origin Leukemia after Allogeneic Stem Cell Transplantation. NGS (Exome) NGS (Exome) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2100004 NANDO:2100004 https://humandbs.dbcls.jp/hum0014 hum0014 オーダーメイド医療の実現プログラム Bio Bank Japan project SNP-chip NGS (WGS、Target Capture) SNP-chip Case-Control NGS (WGS, Target Capture) 非制限公開 制限(Type I) Unrestricted-access Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2100004 NANDO:2100004 https://humandbs.dbcls.jp/hum0130 hum0130 POEMS症候群の骨髄細胞における遺伝子異常の網羅的解析 造血器腫瘍と骨髄ニッチ細胞の遺伝子異常解析による分子病態の解明と新規治療薬開発の基盤構築 Comprehensive genetic analyses of bone marrow cells in POEMS syndrome Analyses of molecular mechanisms of hematological malignancies and bone marrow niche NGS (Exome、Target Capture、RNA-seq、scRNA-seq) NGS (Exome, Target Capture, RNA-seq, scRNA-seq) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2100175 NANDO:2100175 https://humandbs.dbcls.jp/hum0382 hum0382 造血器疾患における遺伝子異常・エピジェネティクス異常の解析 Analysis of genetic and epigenetic abnormalities in hematopoietic diseases NGS (WGS) NGS (WGS) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2100214 NANDO:2100214 https://humandbs.dbcls.jp/hum0069 hum0069 神経筋疾患、ウイルス性疾患におけるRNA発現プロファイル解析 RNA expression profiling of neuromuscular diseases and viral diseases NGS (small RNA-seq) NGS (small RNA-seq) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2100214 NANDO:2100214 https://humandbs.dbcls.jp/hum0423 hum0423 マルチオミックス的アプローチによる炎症性筋疾患の全容解明 Comprehensive elucidation of inflammatory muscle diseases by multi-omics analysis NGS (RNA-seq、snRNA-seq) NGS (RNA-seq, snRNA-seq) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2100259 NANDO:2100259 https://humandbs.dbcls.jp/hum0166 hum0166 炎症性腸疾患患者におけるチオプリン関連副作用とNUDT15遺伝子多型との相関性に関する多施設共同研究(MENDEL Study) Multicenter Evaluation of NUDT15-R139C genotyping efficiency to DEtect thiopurine-induced hair Loss and leukopenia (MENDEL study) SNP-chip SNP-chip 非制限公開 制限(Type I) Unrestricted-access Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200001 NANDO:2200001 https://humandbs.dbcls.jp/hum0251 hum0251 成人フィラデルフィア染色体陰性precursor B細胞性急性リンパ性白血病に対する多剤併用化学療法による第Ⅱ相臨床試験 Phase II clinical trial of adult Philadelphia chromosome-negative precursor B-cell acute lymphocytic leukemia with combination chemotherapy NGS (RNA-seq、Target Capture) NGS (RNA-seq, Target Capture) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200001 NANDO:2200001 https://humandbs.dbcls.jp/hum0318 hum0318 血液疾患のゲノム解析研究 Clinical sequence of hematological malignancy NGS (Target Capture) NGS (Target Capture) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200001 NANDO:2200001 https://humandbs.dbcls.jp/hum0405 hum0405 小児・成人悪性腫瘍がん幹細胞の同定に関する研究 Research on the identification of cancer stem cells for peidatric and adult malignancies NGS (Exome、RNA-seq、small RNA-seq) NGS (Exome, RNA-seq, small RNA-seq) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200003 NANDO:2200003 https://humandbs.dbcls.jp/hum0096 hum0096 造血器腫瘍における遺伝子異常の網羅的解析(小児T細胞性急性リンパ性白血病) Comprehensive analysis of genetic alterations in hematological malignancies NGS (RNA-seq) メチル化アレイ NGS (RNA-seq) Methylation array 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200004 NANDO:2200004 https://humandbs.dbcls.jp/hum0405 hum0405 小児・成人悪性腫瘍がん幹細胞の同定に関する研究 Research on the identification of cancer stem cells for peidatric and adult malignancies NGS (Exome、RNA-seq、small RNA-seq) NGS (Exome, RNA-seq, small RNA-seq) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200014 NANDO:2200014 https://humandbs.dbcls.jp/hum0024 hum0024 造血器腫瘍における 遺伝子異常の網羅的解析 Comprehensive Analysis of Genetic Alterations in Hematological Malignancies NGS (Exome) NGS (Exome) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200014 NANDO:2200014 https://humandbs.dbcls.jp/hum0289 hum0289 慢性骨髄単球性白血病(CMML)における同種移植後再発メカニズムの探索 Mechanisms on relapse after allogeneic hematopoietic cell transplantation in CMML NGS (RNA-seq、Exome) メチル化アレイ NGS (RNA-seq, Exome) Methylation array 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200015 NANDO:2200015 https://humandbs.dbcls.jp/hum0024 hum0024 造血器腫瘍における 遺伝子異常の網羅的解析 Comprehensive Analysis of Genetic Alterations in Hematological Malignancies NGS (Exome) NGS (Exome) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200015 NANDO:2200015 https://humandbs.dbcls.jp/hum0263 hum0263 若年性骨髄単球性白血病における遺伝子異常の網羅的解析 Comprehensive analysis of the abnormality of the genes in juvenile myelomonocytic leukemia NGS (DREAM-seq) NGS (DREAM-seq) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200015 NANDO:2200015 https://humandbs.dbcls.jp/hum0289 hum0289 慢性骨髄単球性白血病(CMML)における同種移植後再発メカニズムの探索 Mechanisms on relapse after allogeneic hematopoietic cell transplantation in CMML NGS (RNA-seq、Exome) メチル化アレイ NGS (RNA-seq, Exome) Methylation array 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200018 NANDO:2200018 https://humandbs.dbcls.jp/hum0465 hum0465 混合形質性急性白血病細胞株の樹立とゲノム解析 Establishment and genomic analysis of mixed phenotypic acute leukemia cell lines NGS (Exome、RNA-seq) NGS (Exome, RNA-seq) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200019 NANDO:2200019 https://humandbs.dbcls.jp/hum0024 hum0024 造血器腫瘍における 遺伝子異常の網羅的解析 Comprehensive Analysis of Genetic Alterations in Hematological Malignancies NGS (Exome) NGS (Exome) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200019 NANDO:2200019 https://humandbs.dbcls.jp/hum0165 hum0165 家族性骨髄異形成症候群の遺伝子解析研究 Genetic analysis of familial myelodysplastic syndromes NGS (Exome) NGS (Exome) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200019 NANDO:2200019 https://humandbs.dbcls.jp/hum0384 hum0384 造血器腫瘍の分子病態の解明と新規治療薬開発の基盤構築 Deciphering molecular mechanisms underlying hematological malignancies and development of novel therapeutic approaches NGS (RNA-seq、Target Capture、ATAC-seq) NGS (RNA-seq, Target Capture, ATAC-seq) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200019 NANDO:2200019 https://humandbs.dbcls.jp/hum0473 hum0473 造血器腫瘍患者の遺伝子解析による発症機序解明研究 血縁ドナーの微量残存骨髄液を正常コントロールとした造血器腫瘍特異的分子発現解析 Elucidation of the pathogenesis of hematopoietic neoplasms via genetic analysis Molecular expression analysis of bone marrow cells from hematopoietic stem cell transplant donors as a normal control NGS (RNA-seq) NGS (RNA-seq) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200020 NANDO:2200020 https://humandbs.dbcls.jp/hum0134 hum0134 Bリンパ腫の転移/再発に特徴的な遺伝子変異の同定 Identification of genetic mutations characteristic for recurrence and metastasis of B cell lymphoma. NGS (Exome) NGS (Exome) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200031 NANDO:2200031 https://humandbs.dbcls.jp/hum0367 hum0367 血液疾患のゲノム解析研究 Clinical sequence of hematological malignancy NGS (Target Capture) NGS (Target Capture) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200040 NANDO:2200040 https://humandbs.dbcls.jp/hum0035 hum0035 固形腫瘍における遺伝子異常の網羅的解析 Genome wide analysis of gene mutations in solid tumors NGS (Exome、Target Capture、RNA-seq) SNP-chip メチル化アレイ NGS (Exome, Target Capture, RNA-seq) SNP-chip Methylation array 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200042 NANDO:2200042 https://humandbs.dbcls.jp/hum0340 hum0340 小児固形腫瘍症例の次世代シークエンサーを用いた網羅的ゲノム解析 Comprehensive genomic analysis using next-generation sequencer for pediatric solid tumor cases NGS (WGS、Target Capture) NGS (WGS, Target Capture) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200045 NANDO:2200045 https://humandbs.dbcls.jp/hum0148 hum0148 泌尿器科腫瘍組織での遺伝子異常と発現解析 Analysis of abnomal character and expression of genes in tissues of urologic carcinomas. NGS (RNA-seq) NGS (RNA-seq) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200045 NANDO:2200045 https://humandbs.dbcls.jp/hum0277 hum0277 泌尿器科領域の腫瘍性疾患の発症、進展、及び薬剤の治療効果に関わる遺伝子の解析 Analysis of genes related to the oncogenesis, progression or effectiveness of drug therapies of urological tumors NGS (scRNA-seq、Exome、RNA-seq、WGS) NGS (scRNA-seq, Exome, RNA-seq, WGS) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200046 NANDO:2200046 https://humandbs.dbcls.jp/hum0035 hum0035 固形腫瘍における遺伝子異常の網羅的解析 Genome wide analysis of gene mutations in solid tumors NGS (Exome、Target Capture、RNA-seq) SNP-chip メチル化アレイ NGS (Exome, Target Capture, RNA-seq) SNP-chip Methylation array 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200046 NANDO:2200046 https://humandbs.dbcls.jp/hum0161 hum0161 シークエンス解析によるがんゲノム研究:肝芽腫 Genome sequencing analysis for hepatoblastoma NGS (WGS) NGS (WGS) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200046 NANDO:2200046 https://humandbs.dbcls.jp/hum0233 hum0233 小児肝癌に対する国際共同臨床試験(PHITT, JPLT4)付随研究 Paediatric Hepatic International Tumour Trial (JPLT4: PHITT) NGS (Exome、RNA-seq、WGBS) SNP-chip メチル化アレイ NGS (Exome, RNA-seq, WGBS) SNP-chip Methylation array 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200047 NANDO:2200047 https://humandbs.dbcls.jp/hum0041 hum0041 肝胆膵癌の早期発見、進行、予後予測、 治療効果予測に関わる因子の研究 Research of factors related to diagnosis, progression, prognosis and treatment of hepato-biliary-pancreatic malignancies NGS (Exome、Target Capture) NGS (Exome, Target Capture) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200047 NANDO:2200047 https://humandbs.dbcls.jp/hum0074 hum0074 テーラーメイド治療を目指した肝炎ウイルスデータベース構築に関する研究 Genome-wide association studies on Hepatitis C virus-related diseases and construction of genome database SNP-chip SNP-chip 非制限公開 Unrestricted-access http://nanbyodata.jp/ontology/NANDO_2200047 NANDO:2200047 https://humandbs.dbcls.jp/hum0075 hum0075 B型肝炎ウイルス感染の病態別における宿主遺伝因子の探索研究 Search for susceptibility genes to hepatitis virus B-related diseases SNP-chip SNP-chip 非制限公開 Unrestricted-access http://nanbyodata.jp/ontology/NANDO_2200047 NANDO:2200047 https://humandbs.dbcls.jp/hum0119 hum0119 NASHの発症、進展を規定するメカニズム解析 Analysis for mechanism of onset and progress for NASH SNP-chip SNP-chip 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200047 NANDO:2200047 https://humandbs.dbcls.jp/hum0138 hum0138 固形腫瘍における遺伝子異常の網羅的解析 Clonal structure and oncogenic potential of liver cirrhosis tissues NGS (Exome、RNA-seq) NGS (Exome, RNA-seq) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200047 NANDO:2200047 https://humandbs.dbcls.jp/hum0158 hum0158 シークエンス解析によるがんゲノム研究:肝臓がん Genome sequencing analysis for liver cancer NGS (WGS、RNA-seq) NGS (WGS, RNA-seq) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200047 NANDO:2200047 https://humandbs.dbcls.jp/hum0161 hum0161 シークエンス解析によるがんゲノム研究:肝芽腫 Genome sequencing analysis for hepatoblastoma NGS (WGS) NGS (WGS) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200047 NANDO:2200047 https://humandbs.dbcls.jp/hum0182 hum0182 全ゲノムシークエンスデータの解析による変異と遺伝的多様性の包括的解析 Comprehansive analysis of somatic mutations and genetic variations with whole genome sequencing NGS (WGS、RNA-seq) NGS (WGS, RNA-seq) 非制限公開 制限(Type I) Unrestricted-access Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200047 NANDO:2200047 https://humandbs.dbcls.jp/hum0187 hum0187 消化器癌のゲノム・遺伝子解析とその臨床病理学的意義の解明 Genomic and genetic analysis of digestive tract cancer and elucidation of its clinicopathological significance. NGS (Target Capture、Exome、RNA-seq) メチル化アレイ NGS (Target Capture, Exome, RNA-seq), Methylation array 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200047 NANDO:2200047 https://humandbs.dbcls.jp/hum0195 hum0195 消化器癌における遺伝子異常についての網羅的解析 Comprehensive genetic analysis of gastrointestinal and hepatobiliary tumor NGS (WGS、Exome、RNA-seq、Target Capture) NGS (WGS, Exome, RNA-seq, Target Capture) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200047 NANDO:2200047 https://humandbs.dbcls.jp/hum0233 hum0233 小児肝癌に対する国際共同臨床試験(PHITT, JPLT4)付随研究 Paediatric Hepatic International Tumour Trial (JPLT4: PHITT) NGS (Exome、RNA-seq、WGBS) SNP-chip メチル化アレイ NGS (Exome, RNA-seq, WGBS) SNP-chip Methylation array 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200047 NANDO:2200047 https://humandbs.dbcls.jp/hum0286 hum0286 非アルコール性脂肪性肝疾患患者における肝癌発症・進展機序の解明 Elucidation of molecular mechanism of NAFLD-HCC NGS (Visium Spatial Gene Expression、Target Capture) 病理画像 NGS (Visium Spatial Gene Expression, Target Capture) Histological image 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200047 NANDO:2200047 https://humandbs.dbcls.jp/hum0306 hum0306 国際連携によるがんゲノムシークエンス解析 (シークエンス解析によるがんゲノム研究) Cancer Genome Sequencing Analysis NGS (WGS) NGS (WGS) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200047 NANDO:2200047 https://humandbs.dbcls.jp/hum0327 hum0327 個別化T細胞受容体遺伝子導入T細胞療法の臨床応用を目指した肝胆膵領域がんにおけるネオアンチゲンおよびそれを認識するT細胞受容体のスクリーニング Screening of neoantigens and neoantigen reactive T cell receptors in hepatobiliary and pancreatic cancer for clinical application of personalized T cell therapy NGS (Exome、RNA-seq) NGS (Exome, RNA-seq) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200047 NANDO:2200047 https://humandbs.dbcls.jp/hum0385 hum0385 混合型肝癌、細胆管細胞癌、Cytokeratin19陽性肝細胞癌、SOX9陽性肝細胞癌の網羅的DNA変異解析 Comprehensive genetic analysis of Combined hepatocellular-cholangiocarcinoma, Cholangiolocarcinoma, Keratin 19-expressing hepatocellular carcinoma, and SOX9-expressing hepatocellular carcinoma NGS (Exome) NGS (Exome) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200048 NANDO:2200048 https://humandbs.dbcls.jp/hum0270 hum0270 ゲノムおよび遺伝子解析に基づく骨軟部腫瘍に特異的な分子病理学的異常の解明と、新規診断および治療法の開発を目指したトランスレーショナル研究 Translational research for elucidating molecular and pathological abnormalities specific to bone and soft tissue tumors based on genomic and genetic analysis, and for developing new diagnostic and therapeutic strategies NGS (Target Capture) NGS (Target Capture) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200052 NANDO:2200052 https://humandbs.dbcls.jp/hum0401 hum0401 創薬をめざした新規骨・軟部肉腫細胞株および疾患モデル動物の開発 Development of cell lines and mouse models of bone and soft tissue sarcoma to establish novel treatment NGS (Exome、RNA-seq) NGS (Exome, RNA-seq) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200056 NANDO:2200056 https://humandbs.dbcls.jp/hum0035 hum0035 固形腫瘍における遺伝子異常の網羅的解析 Genome wide analysis of gene mutations in solid tumors NGS (Exome、Target Capture、RNA-seq) SNP-chip メチル化アレイ NGS (Exome, Target Capture, RNA-seq) SNP-chip Methylation array 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200077 NANDO:2200077 https://humandbs.dbcls.jp/hum0163 hum0163 精神・神経疾患治療薬及びがん治療薬におけるファーマコゲノミクス研究 Pharmacogenomics research for therapeutics in psychiatry, neurology and oncology NGS (Target Capture) SNP-chip NGS (Target Capture) SNP-chip 非制限公開 Unrestricted-access http://nanbyodata.jp/ontology/NANDO_2200077 NANDO:2200077 https://humandbs.dbcls.jp/hum0216 hum0216 消化管癌を含む固形癌患者における免疫状態の解明と臨床的意義に関する研究 新規免疫療法や併用療法開発を目指した固形癌患者の免疫状態の解析 Analyses of immune status of patients with solid tumors including gastrointestinal cancer Investigation of anti-tumor immunological response in solid tumors NGS (Exome) NGS (Exome) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200077 NANDO:2200077 https://humandbs.dbcls.jp/hum0247 hum0247 がん患者免疫状態を反映するがん遺伝子変異の探索 Research for gene mutations in cancer representing immune status of the patients NGS (Exome) NGS (Exome) 非制限公開 制限(Type I) Unrestricted-access Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200077 NANDO:2200077 https://humandbs.dbcls.jp/hum0272 hum0272 メラノーマ等、皮膚腫瘍病変の免疫状態の解析 Analysis of the immune status of melanoma and other skin tumors NGS (Exome、RNA-seq、scRNA-seq、scTCR-seq、Target Capture) NGS (Exome, RNA-seq, scRNA-seq, scTCR-seq, Target Capture) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200077 NANDO:2200077 https://humandbs.dbcls.jp/hum0295 hum0295 皮膚腫瘍の診断と治療効果の評価および経過観察のためのバイオマーカーの探索(前向き観察研究) Search for biomarkers for diagnosis, evaluation of therapeutic effect, and follow-up of skin tumors (prospective observational study) NGS (Amplicon-seq) NGS (Amplicon-seq) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200079 NANDO:2200079 https://humandbs.dbcls.jp/hum0381 hum0381 切除不能または再発胸腺癌に対するニボルマブの多施設共同第II相試験(NCCH1505)附随研究 A biomarker study of a multicenter Phase II Trial of Nivolumab for Unresectable or Recurrent Thymic Carcinoma (NCCH1505) NGS (Target Capture) NGS (Target Capture) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200080 NANDO:2200080 https://humandbs.dbcls.jp/hum0035 hum0035 固形腫瘍における遺伝子異常の網羅的解析 Genome wide analysis of gene mutations in solid tumors NGS (Exome、Target Capture、RNA-seq) SNP-chip メチル化アレイ NGS (Exome, Target Capture, RNA-seq) SNP-chip Methylation array 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200082 NANDO:2200082 https://humandbs.dbcls.jp/hum0035 hum0035 固形腫瘍における遺伝子異常の網羅的解析 Genome wide analysis of gene mutations in solid tumors NGS (Exome、Target Capture、RNA-seq) SNP-chip メチル化アレイ NGS (Exome, Target Capture, RNA-seq) SNP-chip Methylation array 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200087 NANDO:2200087 https://humandbs.dbcls.jp/hum0088 hum0088 腫瘍細胞におけるTGF-βファミリーシグナルの網羅的解析 Global analysis of TGF-beta family signaling in cancer cells NGS (RNA-seq、WGS) NGS (RNA-seq, WGS) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200087 NANDO:2200087 https://humandbs.dbcls.jp/hum0340 hum0340 小児固形腫瘍症例の次世代シークエンサーを用いた網羅的ゲノム解析 Comprehensive genomic analysis using next-generation sequencer for pediatric solid tumor cases NGS (WGS、Target Capture) NGS (WGS, Target Capture) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200089 NANDO:2200089 https://humandbs.dbcls.jp/hum0006 hum0006 脳腫瘍のゲノム・遺伝子解析と その臨床病理学的意義の解明 Genomic and Genetic Analysis of Brain Tumors and Analysis of Their Clinicopathological Significance NGS (Exome、RNA-seq、Target Capture) メチル化アレイ NGS (Exome, RNA-seq, Target Capture) Methylation array 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200091 NANDO:2200091 https://humandbs.dbcls.jp/hum0456 hum0456 傍鞍部頭蓋底腫瘍及び、悪性神経膠腫組織を用いた分子生物学的解析による腫瘍の形成と機能的分化における分子病態の検討 Molecular Pathological exprolation of Tumor Formation and Functional Differentiation Using Parasellar Skull Base Tumors and Malignant Glioma Tissues NGS (scRNA-seq) NGS (scRNA-seq) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200121 NANDO:2200121 https://humandbs.dbcls.jp/hum0476 hum0476 腎臓構成細胞の生物学的機能理解のための先端的解析技術を用いた観察研究 Observational studies using advanced analytical techniques to understand the biological functions of kidney component cells NGS (scRNA-seq、Visium Spatial Gene Expression) 病理画像 NGS (scRNA-seq, Visium Spatial Gene Expression) Histological image 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200226 NANDO:2200226 https://humandbs.dbcls.jp/hum0014 hum0014 オーダーメイド医療の実現プログラム Bio Bank Japan project SNP-chip NGS (WGS、Target Capture) SNP-chip Case-Control NGS (WGS, Target Capture) 非制限公開 制限(Type I) Unrestricted-access Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200228 NANDO:2200228 https://humandbs.dbcls.jp/hum0377 hum0377 不整脈症候群の遺伝子基盤に関する研究 Research on the genetic basis of arrhythmia syndrome NGS (Amplicon-seq) NGS (Amplicon-seq) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200229 NANDO:2200229 https://humandbs.dbcls.jp/hum0404 hum0404 循環器疾患のゲノム解析技術、iPS細胞技術、ゲノム編集技術を用いた病態解明ならびに治療法開発研究 循環器疾患患者由来iPS細胞を用いた病態解明ならびに新規医療技術開発研究 Elucidation of pathology and therapeutic development using genome analysis, iPS cells, and genome editing for cardiovascular diseases Elucidation of pathology and development of novel medical technology using iPS cells derived from patients with cardiovascular disease NGS (scRNA-seq、WGS) NGS (scRNA-seq, WGS) 非制限公開 制限(Type I) Unrestricted-access Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200230 NANDO:2200230 https://humandbs.dbcls.jp/hum0404 hum0404 循環器疾患のゲノム解析技術、iPS細胞技術、ゲノム編集技術を用いた病態解明ならびに治療法開発研究 循環器疾患患者由来iPS細胞を用いた病態解明ならびに新規医療技術開発研究 Elucidation of pathology and therapeutic development using genome analysis, iPS cells, and genome editing for cardiovascular diseases Elucidation of pathology and development of novel medical technology using iPS cells derived from patients with cardiovascular disease NGS (scRNA-seq、WGS) NGS (scRNA-seq, WGS) 非制限公開 制限(Type I) Unrestricted-access Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200248 NANDO:2200248 https://humandbs.dbcls.jp/hum0014 hum0014 オーダーメイド医療の実現プログラム Bio Bank Japan project SNP-chip NGS (WGS、Target Capture) SNP-chip Case-Control NGS (WGS, Target Capture) 非制限公開 制限(Type I) Unrestricted-access Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200286 NANDO:2200286 https://humandbs.dbcls.jp/hum0131 hum0131 発達障害のエピゲノム解析 The epigenetics of neurodevelopmental disorders NGS (RNA-seq) NGS (RNA-seq) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200416 NANDO:2200416 https://humandbs.dbcls.jp/hum0214 hum0214 ヒト免疫系の機能ゲノム学による統合的理解とこれを用いた免疫疾患の発症予防のためのインターベンション戦略の構築 Integrative understanding of human immune system by functional genomics and development of intervention strategies for the prevention of autoimmune diseases NGS (RNA-seq、scRNA-seq) eQTL B細胞受容体レパトア解析 NGS (RNA-seq, scRNA-seq) eQTL BCR repertoire analysis 非制限公開 制限(Type I) Unrestricted-access Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200416 NANDO:2200416 https://humandbs.dbcls.jp/hum0379 hum0379 制御性T細胞特異的エピゲノム誘導による免疫制御の研究 Immune regulation by cotrolling regulatory T cell-specific epigenome NGS (scRNA-seq、scVDJ-seq) NGS (scRNA-seq, scVDJ-seq) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200420 NANDO:2200420 https://humandbs.dbcls.jp/hum0214 hum0214 ヒト免疫系の機能ゲノム学による統合的理解とこれを用いた免疫疾患の発症予防のためのインターベンション戦略の構築 Integrative understanding of human immune system by functional genomics and development of intervention strategies for the prevention of autoimmune diseases NGS (RNA-seq、scRNA-seq) eQTL B細胞受容体レパトア解析 NGS (RNA-seq, scRNA-seq) eQTL BCR repertoire analysis 非制限公開 制限(Type I) Unrestricted-access Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200420 NANDO:2200420 https://humandbs.dbcls.jp/hum0416 hum0416 経時的な多層的オミックス解析を通した免疫難病及びがんにおける生体反応の解明と新規治療法の開発 Elucidation of biological responses in intractable immune disorders and cancer and development of novel therapies through sequential multilevel omics analysis. NGS (CITE-seq、BD Ab-seq、scRNA-seq) シングルセル空間トランスクリプトーム NGS (CITE-seq, BD Ab-seq, scRNA-seq) single-cell spatial transcriptome 非制限公開 Unrestricted-access http://nanbyodata.jp/ontology/NANDO_2200420 NANDO:2200420 https://humandbs.dbcls.jp/hum0492 hum0492 産学連携による免疫炎症性難病の新規医薬品開発を目指した探索研究 Exploratory research aimed at developing new drugs for difficult-to-treat immune-inflammatory diseases through industry-academia collaboration NGS (scRNA-seq/TCR/BCRレパトア解析、Visium Spatial Gene Expression) 病理画像 NGS (scRNA-seq/TCR/BCR repetoire, Visium Spatial Gene Expression) Histological image 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200422 NANDO:2200422 https://humandbs.dbcls.jp/hum0214 hum0214 ヒト免疫系の機能ゲノム学による統合的理解とこれを用いた免疫疾患の発症予防のためのインターベンション戦略の構築 Integrative understanding of human immune system by functional genomics and development of intervention strategies for the prevention of autoimmune diseases NGS (RNA-seq、scRNA-seq) eQTL B細胞受容体レパトア解析 NGS (RNA-seq, scRNA-seq) eQTL BCR repertoire analysis 非制限公開 制限(Type I) Unrestricted-access Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200422 NANDO:2200422 https://humandbs.dbcls.jp/hum0416 hum0416 経時的な多層的オミックス解析を通した免疫難病及びがんにおける生体反応の解明と新規治療法の開発 Elucidation of biological responses in intractable immune disorders and cancer and development of novel therapies through sequential multilevel omics analysis. NGS (CITE-seq、BD Ab-seq、scRNA-seq) シングルセル空間トランスクリプトーム NGS (CITE-seq, BD Ab-seq, scRNA-seq) single-cell spatial transcriptome 非制限公開 Unrestricted-access http://nanbyodata.jp/ontology/NANDO_2200423 NANDO:2200423 https://humandbs.dbcls.jp/hum0214 hum0214 ヒト免疫系の機能ゲノム学による統合的理解とこれを用いた免疫疾患の発症予防のためのインターベンション戦略の構築 Integrative understanding of human immune system by functional genomics and development of intervention strategies for the prevention of autoimmune diseases NGS (RNA-seq、scRNA-seq) eQTL B細胞受容体レパトア解析 NGS (RNA-seq, scRNA-seq) eQTL BCR repertoire analysis 非制限公開 制限(Type I) Unrestricted-access Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200426 NANDO:2200426 https://humandbs.dbcls.jp/hum0416 hum0416 経時的な多層的オミックス解析を通した免疫難病及びがんにおける生体反応の解明と新規治療法の開発 Elucidation of biological responses in intractable immune disorders and cancer and development of novel therapies through sequential multilevel omics analysis. NGS (CITE-seq、BD Ab-seq、scRNA-seq) シングルセル空間トランスクリプトーム NGS (CITE-seq, BD Ab-seq, scRNA-seq) single-cell spatial transcriptome 非制限公開 Unrestricted-access http://nanbyodata.jp/ontology/NANDO_2200429 NANDO:2200429 https://humandbs.dbcls.jp/hum0214 hum0214 ヒト免疫系の機能ゲノム学による統合的理解とこれを用いた免疫疾患の発症予防のためのインターベンション戦略の構築 Integrative understanding of human immune system by functional genomics and development of intervention strategies for the prevention of autoimmune diseases NGS (RNA-seq、scRNA-seq) eQTL B細胞受容体レパトア解析 NGS (RNA-seq, scRNA-seq) eQTL BCR repertoire analysis 非制限公開 制限(Type I) Unrestricted-access Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200429 NANDO:2200429 https://humandbs.dbcls.jp/hum0218 hum0218 全身性強皮症患者の遺伝子発現解析 Gene expression analysis in systemic sclerosis NGS (scRNA-seq) NGS (scRNA-seq) 非制限公開 Unrestricted-access http://nanbyodata.jp/ontology/NANDO_2200429 NANDO:2200429 https://humandbs.dbcls.jp/hum0416 hum0416 経時的な多層的オミックス解析を通した免疫難病及びがんにおける生体反応の解明と新規治療法の開発 Elucidation of biological responses in intractable immune disorders and cancer and development of novel therapies through sequential multilevel omics analysis. NGS (CITE-seq、BD Ab-seq、scRNA-seq) シングルセル空間トランスクリプトーム NGS (CITE-seq, BD Ab-seq, scRNA-seq) single-cell spatial transcriptome 非制限公開 Unrestricted-access http://nanbyodata.jp/ontology/NANDO_2200430 NANDO:2200430 https://humandbs.dbcls.jp/hum0214 hum0214 ヒト免疫系の機能ゲノム学による統合的理解とこれを用いた免疫疾患の発症予防のためのインターベンション戦略の構築 Integrative understanding of human immune system by functional genomics and development of intervention strategies for the prevention of autoimmune diseases NGS (RNA-seq、scRNA-seq) eQTL B細胞受容体レパトア解析 NGS (RNA-seq, scRNA-seq) eQTL BCR repertoire analysis 非制限公開 制限(Type I) Unrestricted-access Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200460 NANDO:2200460 https://humandbs.dbcls.jp/hum0137 hum0137 1型糖尿病関連遺伝子群の多施設共同研究 a multicenter study of susceptibility genes to type 1 diabetes NGS (Target Capture) NGS (Target Capture) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200461 NANDO:2200461 https://humandbs.dbcls.jp/hum0014 hum0014 オーダーメイド医療の実現プログラム Bio Bank Japan project SNP-chip NGS (WGS、Target Capture) SNP-chip Case-Control NGS (WGS, Target Capture) 非制限公開 制限(Type I) Unrestricted-access Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200461 NANDO:2200461 https://humandbs.dbcls.jp/hum0197 hum0197 多層的オミクス解析による疾患病態の解明 Elucidation of disease state by multi-layered omics analysis メタゲノム SNP-chip NGS (WGS、RNA-seq、scRNA-seq) eHHV-6の有無、アネロウイルス量 プロテオミクス Metagenome SNP-chip NGS (WGS, RNA-seq, scRNA-seq) Presence or absence of endogenous herpesvirus 6, anellovirus load proteimics 非制限公開 制限(Type I) Unrestricted-access Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200461 NANDO:2200461 https://humandbs.dbcls.jp/hum0372 hum0372 多層的オミクス解析による疾患病態の解明 メタボリック・シンドローム関連疾患における個別化医療の実現 Elucidation of disease state by multi-layered omics analysis   メタボローム Metabolome 非制限公開 制限(Type I) Unrestricted-access Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200563 NANDO:2200563 https://humandbs.dbcls.jp/hum0221 hum0221 ヒト疾患特異的iPS細胞を用いた遺伝子解析研究 Genetic study using human disease-specific iPS cells NGS (RNA-seq) NGS (RNA-seq) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200579 NANDO:2200579 https://humandbs.dbcls.jp/hum0302 hum0302 iPS細胞の高次特性解析と加工iPS細胞の作製 iPS Cell Advanced Characterization and Development of modified iPS cells NGS (RNA-seq) NGS (RNA-seq) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200602 NANDO:2200602 https://humandbs.dbcls.jp/hum0439 hum0439 脂質異常症に関わる遺伝子と病態との関連の検討 Investigation of the relationship between the genes involved in dyslipidemia and the pathogenesis of the disease NGS (Target Capture) NGS (Target Capture) 非制限公開 Unrestricted-access http://nanbyodata.jp/ontology/NANDO_2200613 NANDO:2200613 https://humandbs.dbcls.jp/hum0434 hum0434 T/NK細胞が関連する各種疾患における遺伝子解析 Genetic analyses in patients with T or NK cells-associated disorders NGS (Exome、Target Capture) NGS (Exome, Target Capture) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200618 NANDO:2200618 https://humandbs.dbcls.jp/hum0378 hum0378 溶血性貧血の病態解明を目指した基礎研究 Basic research to elucidate the pathogenesis of hemolytic anemia NGS (Exome) NGS (Exome) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200636 NANDO:2200636 https://humandbs.dbcls.jp/hum0378 hum0378 溶血性貧血の病態解明を目指した基礎研究 Basic research to elucidate the pathogenesis of hemolytic anemia NGS (Exome) NGS (Exome) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200693 NANDO:2200693 https://humandbs.dbcls.jp/hum0097 hum0097 骨髄不全症候群における血球の質に関する検討 Cytogenetic analysis of hematopoietic cells in bone marrow failure syndrome NGS (Exome) NGS (Exome) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200693 NANDO:2200693 https://humandbs.dbcls.jp/hum0434 hum0434 T/NK細胞が関連する各種疾患における遺伝子解析 Genetic analyses in patients with T or NK cells-associated disorders NGS (Exome、Target Capture) NGS (Exome, Target Capture) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200708 NANDO:2200708 https://humandbs.dbcls.jp/hum0368 hum0368 全ゲノム配列決定によるICF症候群の新規原因遺伝子の探索および機能解析 Identification and functional analysis of novel causative genes of ICF syndrome by whole genome sequencing NGS (PBAT-seq) NGS (PBAT-seq) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200826 NANDO:2200826 https://humandbs.dbcls.jp/hum0375 hum0375 超高速DNAシーケンサーを用いた疾患原因ゲノム領域の同定と情報解析法の確立、および参照配列データの作成に関する研究 identification of disease responsible genome region and establishment of genome information technology by next generation DNA sequencer NGS (Exome) NGS (Exome) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200828 NANDO:2200828 https://humandbs.dbcls.jp/hum0107 hum0107 基底細胞母斑症候群患者からのinduced pluripotent stem (iPS)細胞の樹立および病態の解明、骨移植への臨床応用 Establish induced pluripotent stem (iPS) cells from patients with Gorlin syndrome and elucidate the pathology NGS (Exome、RNA-seq) NGS (Exome, RNA-seq) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200828 NANDO:2200828 https://humandbs.dbcls.jp/hum0276 hum0276 Gorlin症候群に対する汎用型遺伝子診断パネルの開発とリキッドバイオプシーへの応用 Development of a general-purpose genetic diagnostic panel for Gorlin syndrome and its application to liquid biopsy NGS (Target Capture) NGS (Target Capture) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200829 NANDO:2200829 https://humandbs.dbcls.jp/hum0277 hum0277 泌尿器科領域の腫瘍性疾患の発症、進展、及び薬剤の治療効果に関わる遺伝子の解析 Analysis of genes related to the oncogenesis, progression or effectiveness of drug therapies of urological tumors NGS (scRNA-seq、Exome、RNA-seq、WGS) NGS (scRNA-seq, Exome, RNA-seq, WGS) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200850 NANDO:2200850 https://humandbs.dbcls.jp/hum0351 hum0351 画像検査と RNF213 遺伝子検査の融合による閉塞性血管障害の新評価体系の確立 New classification of occlusive cerebrovascular diseases by combining diagnostic imaging and genetic analysis of RNF213 メタゲノム Metagenome 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200864 NANDO:2200864 https://humandbs.dbcls.jp/hum0404 hum0404 循環器疾患のゲノム解析技術、iPS細胞技術、ゲノム編集技術を用いた病態解明ならびに治療法開発研究 循環器疾患患者由来iPS細胞を用いた病態解明ならびに新規医療技術開発研究 Elucidation of pathology and therapeutic development using genome analysis, iPS cells, and genome editing for cardiovascular diseases Elucidation of pathology and development of novel medical technology using iPS cells derived from patients with cardiovascular disease NGS (scRNA-seq、WGS) NGS (scRNA-seq, WGS) 非制限公開 制限(Type I) Unrestricted-access Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200864 NANDO:2200864 https://humandbs.dbcls.jp/hum0514 hum0514 骨格筋メッセンジャーRNAの発現解析による神経・筋疾患の病態解明 Analysis of skeletal muscle messenger RNA expression to elucidate pathophysiology of neuromuscular diseases NGS (RNA-seq) NGS (RNA-seq) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200901 NANDO:2200901 https://humandbs.dbcls.jp/hum0347 hum0347 急性脳症の包括的遺伝子解析 Comprehensive genetic analysis of acute encephalopathy サンガー法 SNP-chip Sanger-seq SNP-chip 非制限公開 Unrestricted-access http://nanbyodata.jp/ontology/NANDO_2200904 NANDO:2200904 https://humandbs.dbcls.jp/hum0379 hum0379 制御性T細胞特異的エピゲノム誘導による免疫制御の研究 Immune regulation by cotrolling regulatory T cell-specific epigenome NGS (scRNA-seq、scVDJ-seq) NGS (scRNA-seq, scVDJ-seq) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200906 NANDO:2200906 https://humandbs.dbcls.jp/hum0321 hum0321 胸腺組織を介した免疫系構築の遺伝子制御に関する研究 Comprehensive analysis of interaction between human gene expression and environmental metagenomes NGS (scRNA-seq) NGS (scRNA-seq) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200906 NANDO:2200906 https://humandbs.dbcls.jp/hum0379 hum0379 制御性T細胞特異的エピゲノム誘導による免疫制御の研究 Immune regulation by cotrolling regulatory T cell-specific epigenome NGS (scRNA-seq、scVDJ-seq) NGS (scRNA-seq, scVDJ-seq) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200920 NANDO:2200920 https://humandbs.dbcls.jp/hum0166 hum0166 炎症性腸疾患患者におけるチオプリン関連副作用とNUDT15遺伝子多型との相関性に関する多施設共同研究(MENDEL Study) Multicenter Evaluation of NUDT15-R139C genotyping efficiency to DEtect thiopurine-induced hair Loss and leukopenia (MENDEL study) SNP-chip SNP-chip 非制限公開 制限(Type I) Unrestricted-access Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200920 NANDO:2200920 https://humandbs.dbcls.jp/hum0197 hum0197 多層的オミクス解析による疾患病態の解明 Elucidation of disease state by multi-layered omics analysis メタゲノム SNP-chip NGS (WGS、RNA-seq、scRNA-seq) eHHV-6の有無、アネロウイルス量 プロテオミクス Metagenome SNP-chip NGS (WGS, RNA-seq, scRNA-seq) Presence or absence of endogenous herpesvirus 6, anellovirus load proteimics 非制限公開 制限(Type I) Unrestricted-access Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200920 NANDO:2200920 https://humandbs.dbcls.jp/hum0454 hum0454 免疫異常に着目した炎症性腸疾患の病因解析および治療反応性解析 Etiological and therapeutic response analysis of inflammatory bowel disease focusing on immune abnormalities Xenium In Situ Gene Expression Xenium In Situ Gene Expression 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200921 NANDO:2200921 https://humandbs.dbcls.jp/hum0125 hum0125 制御性T細胞特異的エピゲノム誘導による免疫制御の研究 Immune regulation by cotrolling regulatory T cell-specific epigenome NGS (RNA-seq) NGS (RNA-seq) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200921 NANDO:2200921 https://humandbs.dbcls.jp/hum0166 hum0166 炎症性腸疾患患者におけるチオプリン関連副作用とNUDT15遺伝子多型との相関性に関する多施設共同研究(MENDEL Study) Multicenter Evaluation of NUDT15-R139C genotyping efficiency to DEtect thiopurine-induced hair Loss and leukopenia (MENDEL study) SNP-chip SNP-chip 非制限公開 制限(Type I) Unrestricted-access Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200921 NANDO:2200921 https://humandbs.dbcls.jp/hum0197 hum0197 多層的オミクス解析による疾患病態の解明 Elucidation of disease state by multi-layered omics analysis メタゲノム SNP-chip NGS (WGS、RNA-seq、scRNA-seq) eHHV-6の有無、アネロウイルス量 プロテオミクス Metagenome SNP-chip NGS (WGS, RNA-seq, scRNA-seq) Presence or absence of endogenous herpesvirus 6, anellovirus load proteimics 非制限公開 制限(Type I) Unrestricted-access Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200921 NANDO:2200921 https://humandbs.dbcls.jp/hum0454 hum0454 免疫異常に着目した炎症性腸疾患の病因解析および治療反応性解析 Etiological and therapeutic response analysis of inflammatory bowel disease focusing on immune abnormalities Xenium In Situ Gene Expression Xenium In Situ Gene Expression 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200930 NANDO:2200930 https://humandbs.dbcls.jp/hum0486 hum0486 胆道閉鎖症およびアラジール症候群特異的iPS細胞を用いた胆管発生およびその障害メカニズムの解明 Bile duct development and its failure mechanisms using biliary atresia and Alagille syndrome-specific iPS cells NGS (WGS) NGS (WGS) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200937 NANDO:2200937 https://humandbs.dbcls.jp/hum0138 hum0138 固形腫瘍における遺伝子異常の網羅的解析 Clonal structure and oncogenic potential of liver cirrhosis tissues NGS (Exome、RNA-seq) NGS (Exome, RNA-seq) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200937 NANDO:2200937 https://humandbs.dbcls.jp/hum0195 hum0195 消化器癌における遺伝子異常についての網羅的解析 Comprehensive genetic analysis of gastrointestinal and hepatobiliary tumor NGS (WGS、Exome、RNA-seq、Target Capture) NGS (WGS, Exome, RNA-seq, Target Capture) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200945 NANDO:2200945 https://humandbs.dbcls.jp/hum0008 hum0008 ヒルシュスプルング病および ヒルシュスプルング類縁疾患の 遺伝要因および発症機構解明に関する研究 Research for genetic causes and mechanisms of Hirschsprung's   NGS (Exome) NGS (Exome) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2200972 NANDO:2200972 https://humandbs.dbcls.jp/hum0129 hum0129 神経疾患患者からのiPS細胞の樹立とそれを用いた疾患解析に関する研究 Research for analyzing mechanistic insight into disease progression of neural disease based on iPS cell technology NGS (ChIP-seq) NGS (ChIP-seq) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2201003 NANDO:2201003 https://humandbs.dbcls.jp/hum0271 hum0271 ハプロ不全により発症する常染色体優性遺伝性疾患における表現型発現の個体差に関する包括的ゲノム解析研究 Comprehensive genome analysis related to individual differences in phenotypic expression in autosomal dominant diseases caused by haploinsufficiency NGS (Target Capture、Target RNA-seq) NGS (Target Capture, Target RNA-seq) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2201006 NANDO:2201006 https://humandbs.dbcls.jp/hum0029 hum0029 Stevens-Johnson症候群に対する 遺伝子多型解析 Study of Genome Polymorphism/Variation on Stevens-Johnson Syndrome SNP-chip SNP-chip Case-Control 非制限公開 Unrestricted-access http://nanbyodata.jp/ontology/NANDO_2201007 NANDO:2201007 https://humandbs.dbcls.jp/hum0029 hum0029 Stevens-Johnson症候群に対する 遺伝子多型解析 Study of Genome Polymorphism/Variation on Stevens-Johnson Syndrome SNP-chip SNP-chip Case-Control 非制限公開 Unrestricted-access http://nanbyodata.jp/ontology/NANDO_2201276 NANDO:2201276 https://humandbs.dbcls.jp/hum0097 hum0097 骨髄不全症候群における血球の質に関する検討 Cytogenetic analysis of hematopoietic cells in bone marrow failure syndrome NGS (Exome) NGS (Exome) 制限(Type I) Controlled-access (Type I) http://nanbyodata.jp/ontology/NANDO_2201322 NANDO:2201322 https://humandbs.dbcls.jp/hum0324 hum0324 脳血管障害及び神経筋難病の遺伝子解析研究 Genetic analysis of cerebrovascular diseases and neuromuscular disorders NGS (WGBS) NGS (WGBS) 制限(Type I) Controlled-access (Type I)